News
Lung cancer and smoking in Tuscany: results of the ACAB study
In 2022 in Tuscany, lung cancer caused 195 and 541 years of life lived with disability (YLD) in women and men, respectively, corresponding to about 9 and 25 YLD per 100,000 people. Of these, about 53% in women and 66% in men were caused by smoking. These data come from the ACAB(Attributable Cancer Burden in Tuscany) study, a project funded by the Region of Tuscany under the 2018 Health Research Call for Proposals conducted by the Institute for the Study and Prevention and Oncology Network...
The future of global health: a perspective on changes in life expectancy and the burden of smoking
Smoking is the leading behavioral risk factor for mortality globally, responsible for more than 175 million deaths and nearly 4.30 billion years of life lost (YLL) from 1990 to 2021. The pace of decline in smoking prevalence has slowed in recent years for many countries, and although strategies to achieve tobacco-free generations have recently been proposed, none have been implemented to date. This is the finding of the recent Global Burden of Disease analysis published in Lancet Public...
Global stroke: the impact of environmental and behavioral factors on a growing crisis
Between 1990 and 2021, globally, the number of people per year who suffered a new stroke increased by 70 percent, deaths caused by stroke increased by 44 percent, and stroke-related health loss, measured in disability-adjusted life years (DALYs), increased by 32 percent. This trend reflects the combined increase in the global population, an aging population, and increased exposure to behavioral and environmental risk factors. Stroke: a preventable but growing disease Despite being highly...
Antibiotic resistance: more than 39 million deaths expected by 2050, according to a GBD Project analysis published in The Lancet
By Sara Moraca A new study published in The Lancet predicts that more than 39 million people could die from antibiotic-resistant infections by 2050. This research, conducted by the Global Research on Antimicrobial Resistance (GRAM) Project, represents the first in-depth global analysis of antimicrobial resistance (AMR) trends between 1990 and 2021 and their projections through mid-century. The study examined 204 countries and territories, drawing a troubling picture for the future of global...
Estimates of antibiotic resistance in Italy and Western Europe in 2019: a comparative analysis based on MICROBE
By 2050, it is estimated that antimicrobial resistance (AMR) will cause 10 million annual deaths worldwide, costing up to $100 trillion. Antibiotic resistance (ABR) is the most significant health threat and, in 2019, caused 1.27 million deaths globally. One in 5 deaths occurred under five years of age, and 6 bacterial pathogens accounted for more than 70% of deaths. Our objective was to compare mortality and disability estimates (DALYs) associated with ABR in 2019 in Italy and Western Europe...
The Burden of Type 1 and 2 Diabetes among adolescents and young adults in 24 Western European countries, 1990-2019
As little is known about the burden of type 1 (T1DM) and type 2 diabetes (T2DM) in adolescents in Western Europe (WE), we aimed to explore their epidemiology among 10-24 year-olds. Estimates were retrieved from the Global Burden of Diseases Study (GBD) 2019. We reported counts, rates per 100,000 population, and percentage changes from 1990 to 2019 for prevalence, incidence and years lived with disability (YLDs) of T1DM and T2DM, and the burden of T2DM in YLDs attributable to high body mass...
Measures of the burden of type 2 diabetes in Italy assessed using AMD data over 12 years
Patients with type 2 diabetes mellitus (T2DM) are rapidly increasing in Italy due to aging, preventable risk factors, and a worsening socioeconomic environment. T2DM and its consequences take a heavy toll on health care systems and the economy, given the costly management, difficulties in coping with daily life, and decreased productivity of patients/workers. Considering the long life expectancy in Italy and a decreasing mortality rate due to T2DM, this study aims to calculate the years lived...
The “burden” of Hepatitis B & C in Europe: analysis by CESP of Milano-Bicocca University on GBD 2019 estimates
In 2016, the World Health Assembly adopted the resolution to eliminate viral hepatitis by 2030. A GBD study led by the University of Milan-Bicocca, published in the journal The Lancet Public Health, aimed to provide an overview of the impact of hepatitis B virus (HBV) and hepatitis C virus (HCV) in Europe and their changes from 2010 to 2019 using estimates from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019 and highlighted what strategies to put in place to move...
Air pollution and health in Italy: analysis of time trends 1990-2019 from GBD 2019 estimates
Air pollution is one of the risk factors assessed by the Global Burden of Disease Study and is of great importance in population health. It actually ranks fourth in terms of impact on a global scale. Since it is known that air quality in Italy has peculiar criticalities, especially in the Po Valley area, we evaluated how the impact estimated by the GBD for our peninsula has varied over time, from 1990 to 2019, with regard to two specific pollutants: atmospheric particulate matter ≤2.5μm...
How to arrive prepared for future pandemics?
In a recent episode of IHME's "Global Health Insights," Joseph Dieleman, professor of Health Metrics Sciences at IHME, and Thomas Bollyky, director of the Council on Foreign Relations (CFR) Global Health program, discuss how to arrive prepared for the next pandemic. The conversation revolves around the findings of an article published in The Lancet, which explores possible contextual factors associated with variability in COVID-19 infection and mortality in the different countries observed....